She knows it won't be an easy journey and she has noticed the impact of not running since December: "I’ve grown in foreign directions and have a body I don’t recognise. I walk around town and find myself breathing heavily. I’m unfit and I have a long road ahead of me."
But she's determined to share her story of #RunningDry and says she would do anything for her mission to save water, "climb literal and figurative mountains, face down my fears, and conquer the evil voices".
She has previously run 40 marathons in 40 days – this expedition will see her run an incredible 4,200km – but she says the success won't be measured in distance so much as making changes among a global community.
Covering such distances, she would like people to run with her – if you would like to join her, get in touch with @minaguli on Twitter or Instagram - or you can show your support from your armchair by following and using #EveryDropCounts.